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  • Acute and Subchronic Toxicity Study of Euphorbia hirta L

    Dec 10, 2013· Despite Euphorbia hirta L. ethnomedicinal benefits, very few studies have described the potential toxicity. The aim of the present study was to evaluate the in vivo toxicity of methanolic extracts of E. hirta.The acute and subchronic oral toxicity of E. hirta was evaluated in Sprague Dawley rats. The extract at a single dose of 5000 mg/kg did not produce treatment related signs of toxicity orAcute and Subchronic Toxicity Study of Euphorbia hirta L,Despite Euphorbia hirta L. ethnomedicinal benefits, very few studies have described the potential toxicity. The aim of the present study was to evaluate the in vivo toxicity of methanolic extracts of E. hirta. The acute and subchronic oral toxicity of E. hirta was evaluated in Sprague Dawley rats. The extract at a single dose of 5000 mg/kg did not produce treatment related signs of toxicity or

  • Toxicity Effects of Methanolic Extract of Euphorbia hirta

    Jan 12, 2018· Toxicity Effects of Methanolic Extract of Euphorbia hirta-Honey Mixture in Albino Rats Ifeanyi Peter Onyeka 1 *, Mohammed M Suleiman 2 and Sunday P Bako 3 1 Department of Biological Sciences, Faculty of Science, Acute toxicity studies showed that LD 50 was greater than 5000 mg/kg.Effects of Ethanolic Leaf Extract of Euphorbia hirta on,Twenty-four hour acute toxicity (LD 50) result of the ethanolic leaf extract of Euphorbia hirta. The different groups for the LD 50 of plant extract were given the different doses (ml) of extract above and the result presented in Table 1 Table 1: Result for the LD 50 experiment for plant extract. Dose (mg/kg) No of death Behavior

  • Acute and Subchronic Toxicity Study of Euphorbia hirta L

    Acute and Subchronic Toxicity Study of Euphorbia hirta L. Methanol Extract in Rats Article (PDF Available) in BioMed Research International 2013(2):182064 · December 2013 with 494 ReadsEffects of Ethanolic Leaf Extract of Euphorbia hirta on,N. nigricollis venom was administered intraperitoneally at a dose of 1414µg/kg body weight of mice and Euphorbia hirta extract was orally administered at a dose of 250mg/kg body weight at different time interval in the in vivo assay. The result for the LD50 of the plant extract showed no mortality.

  • Effects of Ethanolic Leaf Extract of Euphorbia hirta on

    N. nigricollis venom was administered intraperitoneally at a dose of 1414µg/kg body weight of mice and Euphorbia hirta extract was orally administered at a dose of 250mg/kg body weight at different time interval in the in vivo assay. The result for the LD50 of the plant extract showed no mortality.(PDF) Acute toxicity impacts of Euphorbia hirta L extract,Acute toxicity impacts of Euphorbia hirta L extract on behavior, organs body weight index and histopathology of organs of the mice and Artemia salina

  • Gatas-gatas Botobotones Asthma weed Euphorbia hirta

    Gatas-gatas, tawa-tawa, Euphorbia hirta: Study evaluated the in vivo toxicity of methanolic extracts of E. hirta in Sprague Dawley rats. The LD 50 was estimated to be more than 5,000 mg/kg. Results showed long-term oral administration of E. hirta extract for 90 days does not cause sub-chronic toxicity. juice and extract of EuphorbiaResearch Article Acute and Subchronic Toxicity Study of,Research Article Acute and Subchronic Toxicity Study of Euphorbia hirta L. Methanol Extract in Rats KwanYuetPing, 1 IbrahimDarah, 2 YengChen, 3 SubramaniamSreeramanan, 2 andSreenivasanSasidharan 1 Institute for Research in Molecular Medicine (INFORMM), Universiti Sains Malaysia, Minden, Pulau Pinang, Malaysia

  • Antidiabetic and antihyperlipidemic effect of Euphorbia

    oral administration of a dose of Euphorbia hirta (400 mg/kg b. wt) in diabetic groups. Blood glucose levels were determined on 0, 7 th, 14 th and 21st day after oral administration of ethanolic extracts of E. hirta (400 mg/kg). An ethanolic extract of Euphorbia hirta was found to reduce blood sugar in streptozotocin induced diabetic rats.Euphorbia hirta Useful Tropical Plants,Euphorbia hirta is a host to many fungal pathogens and may as such act as a reservoir of pathogenic fungi, which can infect nearby susceptible crops. Trypanosomatid flagellates (Phytomonas spp.) were detected in Euphorbia hirta plants in coconut plantations.

  • Acute toxicity impacts of Euphorbia hirta L extract on

    Acute toxicity impacts of Euphorbia hirta L extract on behavior, organs body weight index and histopathology of organs of the mice and Artemia salina Mohammad Abu Basma Rajeh 1, Yuet Ping Kwan 2, Zuraini Zakaria 1, Lachimanan Yoga Latha 2, Subramanion L Jothy 2, Sreenivasan Sasidharan 2ANTIBACTERIAL ACTIVITIES AND TOXICOLOGICAL ,Journal of American Science, 3(3), 2007, C. C. Ogueke, J. N. Ogbulie, I. C. Okoli, B. N Anyanwu, Antibacterial Activities And Toxicological Potentials Of Crude Ethanolic Extracts OF Euphorbia hirta concentrations of crude ethanolic extract of Euphorbia hirta

  • Assessment of Euphorbia hirta L. Leaf, Flower, Stem and

    Assessment of Euphorbia hirta L. Leaf, Flower, Stem and Root Extracts for Their Antibacterial and Antifungal Activity and Brine Shrimp Lethality Mohammad Abu Basma Rajeh 1, Zakaria Zuraini 1, Sreenivasan Sasidharan 2, Lachimanan Yoga Latha 2 and Santhanam Amutha 2,3,*Euphorbia: Uses, Side Effects, Interactions, Dosage, and,Overview Information Euphorbia is an herb. The parts of the plant that grow above the ground are used to make medicine. Euphorbia is used for breathing disorders including asthma, bronchitis, and

  • Pharmacological Potential of Asthma Weed (Euphorbia hirta

    who used E. hirta extract, found the LD 50 to be over 5000 mg/kg body weight, consequently, a dose of 200, 400 and 800 mg/kg/day were therefore adopted for this study. The animals were divided into five groups of 6 mice each and were orally administered with 200, 400 and 800 mg/kg/day doses of the E. hirta whole plant aqueous-methanolicAcute and Subchronic Toxicity Study of Euphorbia hirta L,Despite Euphorbia hirta L. ethnomedicinal benefits, very few studies have described the potential toxicity. The aim of the present study was to evaluate the in vivo toxicity of methanolic extracts of E. hirta. The acute and subchronic oral toxicity of E. hirta was evaluated in Sprague Dawley rats. The extract at a single dose of 5000 mg/kg did not produce treatment related signs of toxicity or

  • Extracts of Euphorbia hirta Linn. (Euphorbiaceae) and

    Among the 6.25 μg/ml concentrations of E. hirta immobilisation of mff occurred only in the ethyl acetate extract at 4 hours, and also occurred in the chloroform extract at 6 hrs and aqueous extracts at 12 hrs. At 4 hrs the least concentration of each of the E. hirta extract that reduced motile mff numbers to less than 50% was 50 μg/ml of the ethyl acetate extract, 200 μg/ml of the crudeProtective effect of Euphorbia hirta and its components,May 13, 2015· LD 50 was calculated by probit analysis. For venom neutralization studies, different concentrations of E. hirta extract was pre-incubated with twice the LD 50 of venom (w/w) for 1 h at 37 °C with a constant volume of 0.2 ml saline and injected intraperitonially (i.p) to mice (n=4 in a group).

  • Pharmacological Potential of Asthma Weed (Euphorbia hirta

    who used E. hirta extract, found the LD 50 to be over 5000 mg/kg body weight, consequently, a dose of 200, 400 and 800 mg/kg/day were therefore adopted for this study. The animals were divided into five groups of 6 mice each and were orally administered with 200, 400 and 800 mg/kg/day doses of the E. hirta whole plant aqueous-methanolicAcute and Subchronic Toxicity Study of Euphorbia hirta L,Despite Euphorbia hirta L. ethnomedicinal benefits, very few studies have described the potential toxicity. The aim of the present study was to evaluate the in vivo toxicity of methanolic extracts of E. hirta. The acute and subchronic oral toxicity of E. hirta was evaluated in Sprague Dawley rats. The extract at a single dose of 5000 mg/kg did not produce treatment related signs of toxicity or

  • Extracts of Euphorbia hirta Linn. (Euphorbiaceae) and

    Among the 6.25 μg/ml concentrations of E. hirta immobilisation of mff occurred only in the ethyl acetate extract at 4 hours, and also occurred in the chloroform extract at 6 hrs and aqueous extracts at 12 hrs. At 4 hrs the least concentration of each of the E. hirta extract that reduced motile mff numbers to less than 50% was 50 μg/ml of the ethyl acetate extract, 200 μg/ml of the crudeProtective effect of Euphorbia hirta and its components,May 13, 2015· LD 50 was calculated by probit analysis. For venom neutralization studies, different concentrations of E. hirta extract was pre-incubated with twice the LD 50 of venom (w/w) for 1 h at 37 °C with a constant volume of 0.2 ml saline and injected intraperitonially (i.p) to mice (n=4 in a group).

  • A multifaceted peer reviewed journal in the ffeld of

    BEHERA et al: Apopotosis and necrosis of Aqueous Extract of Euphorbia hirta leaves Journal of Young Pharmacists, Vol 8, Issue 3, Jul-Sep, 2016 187 knowledge, no studies exist on the effects of the aqueous extract of Eu- phorbia hirta leaves on the viability and growth of cancer cells.There-fore, the potential of Euphorbia hirta to induce death of human breastFR2639229A1 Novel use of Euphorbia hirta L. in therapy,The present invention relates to the use of Euphorbia Hirta L. for the preparation of pharmaceutical compositions for the treatment of functional disorders and somatic manifestations related to anxiety. Novel use of Euphorbia hirta L. in therapy Google Patents Novel use of Euphorbia hirta L. in therapy 239000006286 aqueous extract

  • Antibacterial activities and toxicological potentials of

    Key words: Euphorbia hirta, ethanolic extract, agar diffusion, inhibition, toxicity. INTRODUCTION Euphorbia hirta belongs to the family Euphorbiaceae. It is a small annual herb common to tropical countries (Soforowa, 1982). It can grow to a height of 40 cm. TheEuphorbia hirta Wikipedia,Euphorbia hirta (sometimes called asthma-plant) is a pantropical weed, possibly native to India. It is a hairy herb that grows in open grasslands, roadsides and pathways. It

  • Antibacterial and oral acute toxicity studies of Euphorbia

    Oral acute toxicity of the extract showed no mortality in Sprague Dawley rats at concentration of 50, 300, 2000 and 5000 mg/kg body weight. Result showed that the LD50 was>5000 mg/kg. The MBC: MIC ration>4, suggesting the crude extract was bactericidal. This study showed that leaves of E. hirta can serve as a potential antibacterial agentAcute toxicity impacts of Euphorbia hirta L extract on,BACKGROUND: The methanol extract of Euphorbia hirta L (Euphorbiaceae), which is used in traditional medicines, was tested for in vivo toxicity. MATERIALS AND METHODS: In vivo brine shrimp lethality assay and oral acute toxicity study at single high dose of 5000 mg/kg and observation for 14 days in mice were used to study the toxic effect of E

  • Phytochemical Screening and antimicrobial study Euphorbia

    Euphorbia hirta is a popular herb in practitioners of traditional herb medicine. Euphorbia hirta is also called asthma herb and pill bearing spurge [14, 15]. The steam of Euphorbia hirta is slender and other reddish in color and covered with yellowish bristly hair especially in young part of Euphorbia hirta.Potential Applications of Euphorbia hirta in Pharmacology,Potential Applications of Euphorbia hirta in Pharmacology 169 content in bronchoalveolar lavage fluid in a 'mild' model of asthma (Singh et al, 2006). Taken together, E. hirta is a very potent herb medicine in treatment of asthma. Ethanol extract of E. hirta has also been shown to

  • Euphorbia hirta plant medicinal uses and images

    Aug 08, 2016· Euphorbia hirta medicinal benefits and pictures Euphorbia hirta is a common herb mostly found in Suriname (a state in South America). It’s a hairy plant and grows as tall as 2’ in length. It bears several flowers and is clustered along with oblong leaves. The leaves appear on either side of the stem. It produces yellow fruits which appear like capsules with reddish seeds.IN VITRO CYTOTOXICITY ACTIVITY AND IN VIVO ORAL ,IN VITRO CYTOTOXICITY ACTIVITY AND IN VIVO ORAL TOXICITY OF Euphorbia hirta by 5.4.2 Effect of E. hirta extract on chromosome aberrations 143 Figure 3.1 The herbarium voucher of Euphorbia hirta 47 Figure 3.2 Microscopy of E. hirta leaf transverse section 50